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Copper’s Functions In the Body

Copper, like iron, assists in electron transfer in the electron-transport chain. It is also an enzyme cofactor essential for iron absorption and transport. The other important function of copper is as an antioxidant. It is naturally present in several foods and is generally accessible as a dietary supplement.[1] A typical adult body has a total copper content of 50-120 mg.[2] The body maintains copper level balance through absorption from the intestine and the release of copper by the liver into bile.[3] Current studies indicate that copper deficiency may be more frequent than previously discovered, while copper toxicity is rare due to conventional diets. [4] Symptoms of mild to moderate copper deficiency are uncommon. More severe copper deficiency can cause anemia due to the lack of iron mobilization for red blood cell synthesis. Other signs and symptoms include growth retardation in children and neurological problems because copper is a cofactor for an enzyme that synthesizes myelin, which surrounds many nerves.

Dietary Reference Intakes for Copper

Table 11.4: Dietary Reference Intakes (DRI) Values for Copper (μg/day)[5]
Life stage group RDA (μg/day) UL
Infants (0-12 months) ND1
Children (1-3 years) 340 1,000
Children (4-8 years) 440 3,000
Children (9-13 years) 700 5,000
Adolescents (14-18 years) 890 8,000
Adults (>18 years) 900 10,000

1 Not Determinable

Dietary Sources of Copper

Copper is distributed in many foods and is abundant in organ meats, seafoods, nuts, and seeds. Wheat bran cereals, whole grains, and cocoa products are also good sources of copper. The absorption of copper from foods may be reduced by excess intakes of zinc and the amino acid histidine, in addition to high intakes of iron and fructose. Copper is also available as part of other ingredients in a multimineral supplement or in a copper-only supplement. Dietary supplements containing copper typically range from a few micrograms to 15 mg.[6]


Learning Activities

Technology Note: The second edition of the Human Nutrition Open Educational Resource (OER) textbook features interactive learning activities.  These activities are available in the web-based textbook and are not in downloadable versions (EPUB, Digital PDF, Print_PDF, or Open Document).

Learning activities may be used across various mobile devices; however, for the best user experience, it is strongly recommended that users complete these activities using a desktop or laptop computer.


  1. Collins, J.F. "Copper". In: Ross, A.C., et al. (2014). Modern Nutrition in Health and Disease. 11th ed. Baltimore, MD: Lippincott Williams & Wilkins; 206-16.
  2. Prohaska, J.R. Copper. In: Erdman, J.W., et al. (2012). Present Knowledge in Nutrition. 10th ed. Washington, DC: Wiley-Blackwell; 540-53.
  3. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Institute of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK222312/. Published January 9, 2001. Accessed July 23, 2025.
  4. de Romaña, D. L., Olivares, M., Uauy, R., & Araya, M. (2011). Risks and benefits of copper in light of new insights into copper homeostasis. Journal of Trace Elements in Medicine and Biology: Organ of the Society for Minerals and Trace Elements (GMS), 25 (1), 3–13.https://doi.org/10.1016/j.jtemb.2010.11.004. Accessed August 14, 2025.
  5. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Institute of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK222299/#ddd00229. Published January 9, 2001. Accessed July 23, 2025.
  6. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Institute of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK222312/. Published January 9, 2001. Accessed July 23, 2025.
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