93 math
LD = SSC ✕ VdB
MD = SSC ✕ CL ✕ DIB
Formula Legend: LD = loading dose; MD = maintenance dose; SSC = desired steady-state concentration of the drug; Vd = volume of distribution; B = drug bioavailability; CL = clearance; DI = dosing interval
[latex]LD = SSC ✕ Vd/B[/latex]
[latex]MD = SSC ✕ CL ✕ DIB[/latex]
Formula Legend: LD = loading dose; MD = maintenance dose; SSC = desired steady-state concentration of the drug; Vd = volume of distribution; B = drug bioavailability; CL = clearance; DI = dosing interval