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93 math

LD = SSC ✕ VdB
MD = SSC ✕ CL ✕ DIB
Formula Legend: LD = loading dose; MD = maintenance dose; SSC = desired steady-state concentration of the drug; Vd = volume of distribution; B = drug bioavailability; CL = clearance; DI = dosing interval

 

[latex]LD = SSC ✕ Vd/B[/latex]

[latex]MD = SSC ✕ CL ✕  DIB[/latex]

Formula Legend: LD = loading dose; MD = maintenance dose; SSC = desired steady-state concentration of the drug; Vd = volume of distribution; B = drug bioavailability; CL = clearance; DI = dosing interval

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